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Microfluidic chip with bioimpedance sensor to study blood rheology

Settembre 25 @ 14:30 - 15:30

Giovedì 25 settembre si terrà un seminario presso l’aula Grandori (Edificio 4 – piano seminterrato) alle ore 14:30 dal titolo “Microfluidic chip with bioimpedance sensor to study blood rheology”.

Il seminario sarà tenuto dal Prof. Olivier Francais, ESIEE Paris.

Abstract

Microfluidic chips are promising tools for studying blood rheology in the context of diseases such as sickle cell anemia. These miniaturized devices can mimic the geometry and environment of blood capillaries, allowing precise control of flow and characterization of red blood cells. The integration of electrodes into these chips allows the electrical impedance of blood to be measured, providing a means of quantifying red blood cell properties such as deformability and stiffness. This approach, combining microfluidics and bioimpedance, paves the way for new methods of diagnosis, treatment monitoring, and therapeutic molecule screening by providing essential information on the behavior of blood cells at the single red blood cell level.

Speaker’s bio
Olivier FRANCAIS is a full Professor at ESIEE Paris, engineering school member of Université Gustave Eiffel (France), with the position of academic Dean. He is member of the “Health, Energy, Environment” department where he teaches Applied Physics, Instrumentation and Micro-electronic Technologies for Lab on a Chip.
He conducts his research at the ESYCOM laboratory (CNRS UMR 9007) in the field of sensors for Health and Lab-On-a-Chip. He is more specifically interested in the development of interfaces for analysis of biological species within microfluidic environment, taking benefits of their dielectric properties.
He is an expert concerning electric parameters extraction within microfluidic devices from bio-impedance measurement at low frequency range (Hz to several MHz) and in dielectric characterisation of biological materials at higher frequency (up to several GHz). During his career, he has developed several technology lines in the field on microfluidics where he has acquired an international expertise. He masters the clean room facilities in order to conduct research and innovation for Lab On a Chip applications.

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